Retrograde Transport Pathway. Control Systems of Membrane Transport at the Interface between the This pathway may be very inefficient, but the extreme potency of these toxins ensures that a lethal amount enters the cytosol. The idea that host factors might potentially shuttle these toxins into cells stimulated the search for endogenous client.
Figure 10 from Rab9dependent retrograde transport and endosomal from www.semanticscholar.org
This pathway may be very inefficient, but the extreme potency of these toxins ensures that a lethal amount enters the cytosol. In fact, the analysis of such toxins led to the discovery and description of retrograde transport pathways involved in endosome-to-Golgi transport (Olsnes and Pihl, 1972; Montanaro et al., 1973; Gonatas et al., 1975)
Figure 10 from Rab9dependent retrograde transport and endosomal
In fact, the analysis of such toxins led to the discovery and description of retrograde transport pathways involved in endosome-to-Golgi transport (Olsnes and Pihl, 1972; Montanaro et al., 1973; Gonatas et al., 1975) The anterograde pathway, from the endoplasmic reticulum through the trans-Golgi network to the cell surface, is utilized by trans-membrane and secretory proteins.The retrograde pathway, which directs traffic in the opposite direction, is used following endocytosis of exogenous molecules and recycling of membrane proteins. The retrograde transport of membrane proteins from endosomes to the trans-Golgi network (TGN) is essential for internalization and recycling of membrane proteins which control a variety of physiological processes including (i) lysosomal biogenesis, (ii) ion and glucose transport, (iii) processing and secretion of polypeptide precursors and (iv) secretion of signaling proteins that regulate.
Retrograde signalling pathways from the chloroplast to the nucleus. Retrograde transport is shown starting from a coated endosome, which is an intermediate in the maturation between early and late endosomes 27,28.The coated endosome is connected to a vast 'tubular. This pathway may be very inefficient, but the extreme potency of these toxins ensures that a lethal amount enters the cytosol.
Transport intermediates and regulators of the GolgitoER retrograde. In fact, the analysis of such toxins led to the discovery and description of retrograde transport pathways involved in endosome-to-Golgi transport (Olsnes and Pihl, 1972; Montanaro et al., 1973; Gonatas et al., 1975) Mechanistic studies that explore the molecular machinery involved in this retrograde trafficking route are shedding light on the functions of transport proteins and are providing fresh.